High panx1 expression leads to neutrophil recruitment and the formation of a high adenosine immunosuppressive tumor microenvironment in basal-like breast cancer

HIGHLIGHTS

• who: Wuzhen Chen and colleagues from the Department of Surgery (Surgical Oncology), Second Affiliated Hospital, Zhejiang University School of Hangzhou, China have published the research work: High PANX1 Expression Leads to Neutrophil Recruitment and the Formation of a High Adenosine Immunosuppressive Tumor Microenvironment in Basal-like Breast Cancer, in the Journal: Cancers 2022, 3369 of 12/04/2021
• what: The authors investigated the effect of PANX1 in basal-like breast cancer primary lesions. This study demonstrated that TANs expressing high levels of ENTPD1/NT5E could promote the hydrolysis of exATP to exADO to aggravate the . . .
  

   

  

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