Dub1 suppresses hippo signaling by modulating taz protein expression in gastric cancer

HIGHLIGHTS

  • who: Dehai Wang from the Department of General Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Shandong Province, People's Republic of China have published the research work: DUB1 suppresses Hippo signaling by modulating TAZ protein expression in gastric cancer, in the Journal: (JOURNAL)
  • what: The authors propose that inhibition of DUB1 expression or pharmaceutical targeting of DUB1 function could be a promising strategy to suppress Hippo/TAZ-driven gastric cancers. Considering these results collectively with the conclusion that DUB1 stabilizes TAZ in cancer progression, the authors propose that targeting DUB1 could block . . .

     

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