Discovery of a novel alk/ros1/fak inhibitor, apg-2449, in preclinical non-small cell lung cancer and ovarian cancer models

HIGHLIGHTS

  • who: Douglas D. Fang from the China for Therapeutic Innovation, University of Michigan, Huron Parkway have published the Article: Discovery of a novel ALK/ROS1/FAK inhibitor, APG-2449, in preclinical non-small cell lung cancer and ovarian cancer models, in the Journal: (JOURNAL)
  • what: Taken together the studies demonstrate that APG-2449 exerts potent and durable antitumor activity in human NSCLC and ovarian tumor models when administered alone or in combination with other A phase 1 clinical trial has been initiated to evaluate the safety and preliminary efficacy of APG-2449 in patients with . . .

     

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