Animal models for autoimmune hepatitis: are current models good enough?

HIGHLIGHTS

  • who: Urs Christen from the University of Bologna Department of Medical and Surgical Sciences, Italy have published the Article: Animal Models for Autoimmune Hepatitis: Are Current Models Good Enough?, in the Journal: (JOURNAL) of 17/03/2022

SUMMARY

    Thereby, liver-resident cells, including hepatic stellate cells July 2022 | Volume 13 | Article 898615 Model Improvement in Autoimmune Hepatitis (HSC) and liver sinusoidal endothelial cells (LSEC) seem to play an important role by inducing T_cell inactivation or apoptosis as well as by expanding regulatory T_cells (Treg). Ectopic hepatic expression of myelin basic protein (MBP), a . . .

     

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