The usefulness of in vitro percutaneous absorption experiments applying the infinite dose technique to predict in vivo plasma levels: comparison of model-predicted and observed plasma concentrations of nortriptyline in rats

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  • who: Iris Usach and collaborators from the Department of Pharmacy and Pharmaceutical Technology and Parasitology, University of Valencia, Burjassot have published the Article: The Usefulness of In Vitro Percutaneous Absorption Experiments Applying the Infinite Dose Technique to Predict In Vivo Plasma Levels: Comparison of Model-Predicted and Observed Plasma Concentrations of Nortriptyline in Rats, in the Journal: Pharmaceutics 2022, 14, 1457. of /2022/
  • what: The aims of this study were to evaluate the feasibility of a nortriptyline (NT) formulation for transdermal administration and to assess the usefulness of an estimated kinetic parameter (kout ) using the . . .

     

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