HIGHLIGHTS
- who: Chia-Hung Chien from the Department of Oncology, National Kung University Hospital, College of Medicine, National Kung University, Tainan, Taiwan have published the Article: SH3GLB1-related autophagy mediates mitochondrial metabolism to acquire resistance against temozolomide in glioblastoma, in the Journal: (JOURNAL)
- what: Results from this study showed that SH3GLB1 enhances tumor resistance in TMZ conditions, with reduced activation of caspase 3.
- how: The expression fold change and significance level (p-value) of mitochondria-related gene_expression between primary and resistant GBM RNA-sequencing data were calculated. For genetic analysis based on molecular functioning . . .
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