Metap1 and metap2 drive cell selectivity for a potent anti-

HIGHLIGHTS

  • who: Top from the Institute for Integrative Biology of the Cell (I BC), CEA, CNRS, UnivParis-Sud, UnivParis-Saclay, Gif-sur-Yvette , France have published the Article: MetAP1 and MetAP2 drive cell selectivity for a potent anti-, in the Journal: (JOURNAL)
  • what: The authors compared fumagillin-sensitive and -insensitive lines.
  • how: This result is entirely consistent with previous reports of a clear decrease in_vitro by at least one order of magnitude for substrates with a proline residue in the P2' position even if the second amino_acid generally results in highly efficient NME . The . . .

     

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