Dysregulation of iron metabolism in cholangiocarcinoma stem-like cells

HIGHLIGHTS

  • who: Chiara Raggi from the (UNIVERSITY) have published the research: Dysregulation of Iron Metabolism in Cholangiocarcinoma Stem-like Cells, in the Journal: (JOURNAL) of 22/09/2017
  • what: The authors focused on CCLP1 and CCA4 cell lines, which were treated with ferric ammonium citrate (FAC) or the iron chelator desferrioxamine (DFO) either as MON or SPH according to the experimental design illustrated in Fig 2a. The authors found a typical pattern (H ferritin low-TfR1 high), indicative of low iron levels, in CCA MON and when the authors compared tumour tissue with the surrounding healthy . . .

     

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