The mammalian ulk1 complex and autophagy initiation

HIGHLIGHTS

  • who: The mammalian ULK from the University of have published the Article: The mammalian ULK1 complex and autophagy initiation, in the Journal: (JOURNAL) of 12/Dec/2017
  • what: In this artcile, the authors focus on the regulation of the ULK1 complex during autophagy initiation.

SUMMARY

    Autophagy is an evolutionarily conserved homoeostatic process that serves as a quality_control mechanism as well as a recycling pathway. The very first autophagy-specific complex that comes into play is the ULK1 (unc-51-like kinase 1) complex, consisting of ULK1 itself, ATG (autophagy-related protein . . .

     

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