Licensed and unlicensed nk cells: differential roles in cancer and viral control

HIGHLIGHTS

  • who: Andrew P. Makrigiannis from the Department of Biochemistry, Microbiology and, University of Ottawa, Ottawa, ON, Canada, College of Applied have published the article: Licensed and Unlicensed NK Cells: Differential Roles in Cancer and Viral Control, in the Journal: (JOURNAL)
  • what: While other inhibitory receptors, such as NKG2A, have been shown to play a role in NK cell licensing as well , the focus of the review will be on the dual role of the Ly49 family receptors on NK cells during target cell recognition and immune evasion. exhibited a more robust responsiveness and cytokine production . . .

     

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