Therapeutic targeting of cancer stem cells

HIGHLIGHTS

  • who: Ruggero De Maria from the DepartmentItaly University of have published the paper: Therapeutic targeting of cancer stem cells, in the Journal: (JOURNAL)
  • what: Mounting evidence points to CSCs as responsible for tumor ­generation and treatment failure.
  • future: Recent breakthroughs in translational oncology are opening new perspectives for the treatment of cancer.

SUMMARY

    The "cancer stem_cell model" has captured great interest only in recent years following the isolation of a rare cellular fraction of leukemia-initiating cells with stem_cell-like features (Bonnet and Dick, 1997). Ever since, this concept . . .

     

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