The consequences of chromosome segregation errors in mitosis and meiosis

HIGHLIGHTS

  • who: Tamara Potapova and Gary J. Gorbsky from the Oklahoma City, OK, USA have published the research: The Consequences of Chromosome Segregation Errors in Mitosis and Meiosis, in the Journal: (JOURNAL)
  • what: This approach demonstrated that tetraploid cells were tumorigenic when injected in immunodeficient mice and gave rise to malignant aneuploid cells, while isogenic diploid cells did not .
  • how: This review describes the consequences of mitotic and meiotic errors focusing on novel concepts and human health.
  • future: Understanding the positive and negative consequences of spindle multipolarity remains an important topic for . . .

     

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