HIGHLIGHTS
- who: Adham Safieddine from the University of have published the Article: A choreography of centrosomal mRNAs reveals a conserved localization mechanism involving active polysome transport, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: Remarkably, all eight mRNAs required synthesis of the nascent protein to localize and, by imaging single ASPM and NUMA1 mRNAs and polysomes, the authors demonstrate that localization occurs by active_transport of polysomes. To investigate how mRNAs localize to centrosomes in more detail, the authors focused on ASPM and first asked whether the 5′ and 3′ UTRs were necessary for its localization. The . . .
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