Clostridium difficile: new insights into the evolution of the pathogenicity locus

HIGHLIGHTS

• who: Marc Monot from the Laboratoire have published the research work: Clostridium difficile: New Insights into the Evolution of the Pathogenicity Locus, in the Journal: Scientific Reports Scientific Reports
• what: The analysis shows that both genes are conserved in RA09-70 and that 51 bases of the intergenic region were lost compared to the same region in the CD630 strain.
• how: This result was negative using the MRC-5 cell cytotoxicity assay which detects TcdB only suggesting that the RA09-070 strain produced TcdA but not TcdB. This results was consistent with the . . .
  

   

  

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