Cyclosporine a treatment inhibits abcc6-dependent cardiac necrosis and calcification following coxsackievirus b3 infection in mice

HIGHLIGHTS

  • who: Jennifer Marton and collaborators from the Department of Human Genetics and Complex Traits Group, McGill University, Canada have published the paper: Cyclosporine A Treatment Inhibits Abcc6-Dependent Cardiac Necrosis and Calcification following Coxsackievirus B3 Infection in Mice, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0138222]. September 16, 2015 of /1371/
  • what: The authors aimed to identify genes that modulate cardiopathology CVB3 infection. Altogether the work demonstrates that mutations in Abcc6 render mice more susceptible to cardiac CVB3 infection. The authors aimed to phenotype at least 5-10 mice per group. The . . .

     

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