Analysis of the role of igf2 in adrenal tumour development in transgenic mouse models

HIGHLIGHTS

• who: Coralie Drelon et al. from the Department of Endocrinology, Reference Center for Rare Adrenal Diseases, Paris, France, Inserm UMR636, Nice, France, Centre Hospitalier Universitaire, ServiceEditor: Zoran Culig, Innsbruck Medical University, Austria have published the research: Analysis of the Role of Igf2 in Adrenal Tumour Development in Transgenic Mouse Models, in the Journal: PLOS ONE | www.plosone.org of August/28,/2012
• what: The analysis shows that despite overexpression levels ranging from 7 (basal) to 87 (ACTH-induced) fold Igf2 has no tumour initiating potential in the adrenal cortex. The authors show that the combination . . .
  

   

  

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