HIGHLIGHTS
- who: Valentyn Oksenych and colleagues from the Toulouse, France have published the research work: Histone Methyltransferase DOT1L Drives Recovery of Gene Expression after a Genotoxic Attack, in the Journal: (JOURNAL) of May/18,/2013
- what: The authors show that knocking-out of the histone methyltransferase DOT1L in mouse embryonic fibroblasts (MEFDOT1L) leads to a UV hypersensitivity coupled to a deficient recovery of transcription initiation after UV irradiation. DOT1L promotes transcription recovery after UV irradiation Next the authors aimed to determine the global RNA synthesis of MEF cells after irradiation using the recovery of RNA synthesis . . .
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