Noise expands the response range of the bacillus subtilis competence circuit

HIGHLIGHTS

• who: Andrew Mugler and colleagues from the Department of Physics and Astronomy, Purdue University, West Lafayette, Indiana, United States of have published the research: Noise Expands the Response Range of the Bacillus subtilis Competence Circuit, in the Journal: (JOURNAL) of August/30,/2015
• what: Using stochastic modeling and fluorescence microscopy the authors show that this larger noise allows cells to exit terminal phenotypic states which expands the range of stress levels to which cells are responsive and leads to phenotypic heterogeneity at the population level. Since a dynamic response is thought to be optimal for . . .
  

   

  

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