Autocatalytic association of proteins by covalent bond formation: a bio molecular welding toolbox derived from a bacterial adhesin

HIGHLIGHTS

  • who: J. Bonnet from the (UNIVERSITY) have published the paper: Autocatalytic association of proteins by covalent bond formation: a Bio Molecular Welding toolbox derived from a bacterial adhesin, in the Journal: (JOURNAL) of 02/03/2017
  • what: Based on the crystal_structure of RrgA, the Streptococcus pneumoniae pilus adhesin, the authors provide evidence that two engineered protein fragments retain their ability to associate covalently with high specificity, in_vivo and in_vitro, once isolated from the parent protein. The authors demonstrate biotechnological applications related to antibody production, nanoassembly and cell-surface labeling based on this process the authors . . .

     

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