Palmitic and stearic acids inhibit chaperone-mediated autophagy (cma) in pomc-like neurons in vitro

HIGHLIGHTS

• who: Rodrigo Espinosa and collaborators from the Centro Ciencia and Vida, Fundación Ciencia and Vida, AvdaZañartu, Ñuñoa, ChileAdvanced Center for Chronic Diseases (ACCDiS), Facultad Ciencias Químicas y Farmacéuticas and Facultad have published the article: Palmitic and Stearic Acids Inhibit Chaperone-Mediated Autophagy (CMA) in POMC-like Neurons In Vitro, in the Journal: (JOURNAL)
• what: The authors show in vitro that the exposure of POMC neurons to PA or SA also inhibits CMA possibly by decreasing the total and lysosomal LAMP2A protein levels. The authors show that CMA activity is important . . .
  

   

  

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