Mathematical deconvolution of car t-cell proliferation and exhaustion from real-time killing assay data

HIGHLIGHTS

  • who: Russell C. Rockne et al. from the Department of Computational and Quantitative Medicine, Division of Mathematical Oncology, Department of Hope National Medical Center, Duarte, CA, USA Department of, University of California, Riverside, CA, USA have published the paper: Mathematical deconvolution of CAR T-cell proliferation and exhaustion from real-time killing assay data, in the Journal: (JOURNAL) of 19/07/2022
  • what: The authors developed the CARRGO model with the aim of understanding CAR T-cell efficacy in terms of rates of killing, proliferation, exhaustion, and persistence with a real-time cell analyser in . . .

     

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