Random mutagenesis of the camp chemoattractant receptor, car1, of dictyostelium

HIGHLIGHTS

• who: JacquelineL.S. Milne from the (UNIVERSITY) have published the paper: Random Mutagenesis of the cAMP Chemoattractant Receptor, cAR1, of Dictyostelium, in the Journal: (JOURNAL) of August/16,/1996
• what: In this study, 22 individual mutants were characterized for their ability to carry out G protein-dependent and -independent signal_transduction. The authors propose that cAMP binding to cAR1 leads to an activated state of the receptor, L-cAR1*, which is able to interact with a receptor kinase.

SUMMARY

To further characterize signal_transduction through cAR1, the authors performed random mutagenesis of the . . .

 



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