Mechanisms underlying the action and synergism of trastuzumab and pertuzumab in targeting her2-positive breast cancer

HIGHLIGHTS

• who: Babak Nami et al. from the (UNIVERSITY) have published the article: Mechanisms Underlying the Action and Synergism of Trastuzumab and Pertuzumab in Targeting HER2-Positive Breast Cancer, in the Journal: Cancers 2018, 10, x FOR PEER REVIEW of /2018/
• what: The approval of trastuzumab in treating breast cancer changes the paradigm of breast cancer treatment. the the effectiveness and overcome the resistance, pertuzumab was later introduced treatment.
• future: Trastuzumab strong ADCCstrong and blocks of active p95HER2 HER2-signaling cascades.stimulates Trastuzumab stimulates ADCCthe andgeneration blocks the generation of active fragments by inhibiting . . .
  

   

  

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