Znf354c mediated by dnmt1 ameliorates lung ischemia- reperfusion oxidative stress injury by reducing tfpi promoter methylation to upregulate tfpi

HIGHLIGHTS

  • who: Qi Shi and colleagues from the Department of Thoracic and Cardiovascular Surgery, Huashan Hospital, Affiliated with Fudan University, Shanghai, China have published the paper: ZNF354C Mediated by DNMT1 Ameliorates Lung Ischemia- Reperfusion Oxidative Stress Injury by Reducing TFPI Promoter Methylation to Upregulate TFPI, in the Journal: Oxidative Medicine and Cellular Longevity of 19/07/2022
  • what: The authors aim to explore the molecular mechanism of lung I/R injury (LIRI). The study showed that ZNF354C could interact with TFPI, and upregulate TFPI by preventing TFPI promoter methylation in OGD/R-induced HUVECs. This research . . .

     

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