Rpd3l and hda1 histone deacetylases facilitate repair of broken forks by promoting sister chromatid cohesion

HIGHLIGHTS

  • who: Pedro Ortega from the Universidad de Sevilla Olavide, Seville, Spain have published the article: Rpd3L and Hda1 histone deacetylases facilitate repair of broken forks by promoting sister chromatid cohesion, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: Interestingly, the authors show that both HDACs contribute to SCR by facilitating cohesin loading and promoting sister chromatid cohesion. The authors show here an epigenetic regulation of the repair of replicationborn DSBs by the modulation of sister chromatid cohesion. The authors demonstrate that this occurs through a role of these HDACs in sister chromatid cohesion by facilitating . . .

     

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