A stable and reproducible human blood-brain barrier model derived from hematopoietic stem cells

HIGHLIGHTS

  • who: Romeo Cecchelli and colleagues from the Blood Brain Barrier Laboratory, University of Artois, Lens, France, CNC, Center of Neurosciences and Cell Biology, University of Coimbra, Coimbra, Portugal have published the research work: A Stable and Reproducible Human Blood-Brain Barrier Model Derived from Hematopoietic Stem Cells, in the Journal: PLOS ONE | www.plosone.org of June/17,/2014
  • what: The authors provide evidence that Wnt/b-catenin signaling pathway mediates in part the BBB inductive properties of pericytes. The authors report a general and relatively easy method to generate a human BBB model using . . .

     

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