Gene expression profiling discerns molecular pathways elicited by ligand signaling to enhance the specification of embryonic stem cells into skeletal muscle lineage

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• who: Katherine Dixon from the The displacement of repressive protein complexes, such as SUZ12, is affected by the specific RAR isotype [62]The transcription of RA target genes also depends on the ability of RAR-RXR to recruit coactivators, and the type of coregulator bound to RAR-RXR, such as pCIP, p, or p300, affects the activation of target genes [25]. DNAbinding by RAR is cell type-specific, and most binding sites are occupied in the absence of RA [63]. Furthermore, the influence of RA is promoter-specific, suggesting diverse transcriptional potential of RARs even within specific . . .
  

   

  

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