Activation of the phosphatidylinositol 3-kinase/akt signaling pathway by retinoic acid is required for neural differentiation of sh-sy5y human neuroblastoma cells*

HIGHLIGHTS

• who: Gracia Lo̕pez-Carballo from the (UNIVERSITY) have published the paper: Activation of the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway by Retinoic Acid Is Required for Neural Differentiation of SH-SY5Y Human Neuroblastoma Cells*, in the Journal: (JOURNAL) of February/25,/2002
• what: The authors show that the mRNA levels of the differentiation-inhibiting basic helix-loophelix transcription factors ID1, ID2, and ID3 are downregulated during RA-induced differentiation of SHSY5Y cells. The authors propose that RA, by activating the PI3K/Akt signaling pathway, plays an important role in the regulation of neuronal cell . . .
  

   

  

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