Inflammation-induced inhibition of chaperone-mediated autophagy maintains the immunosuppressive function of murine mesenchymal stromal cells

HIGHLIGHTS

  • who: Jie Zhang from the (UNIVERSITY) have published the research work: Inflammation-induced inhibition of chaperone-mediated autophagy maintains the immunosuppressive function of murine mesenchymal stromal cells, in the Journal: (JOURNAL)
  • what: The authors found that, CMA-deficient MSCs exhibited a better curative effect on liver injury with decreased inflammation compared to that of SCR-MSCs. This study not only enriched the basic knowledge of the immunoregulatory plasticity of MSCs but also provided a new intervention target to improve the clinical therapeutic efficacy of MSCs.
  • how: The results showed that the number of . . .

     

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