HIGHLIGHTS
- who: Marie-Solenne Felix and colleagues from the Université Paris-Saclay, CEA, CNRS, Inserm, BioMaps, Service Hospitalier Frédéric Joliot have published the paper: Ultrasound-Mediated Blood-Brain Barrier Opening Improves Whole Brain Gene Delivery in Mice, in the Journal: Pharmaceutics 2021, 1245 of /2021/
- what: While most studies focus on a specific targeted area of the brain this work proposes to permeabilize the entire brain for gene therapy in several pathologies. The aim of this study was to develop a whole-brain BBB-opening protocol, both safe and effective, using a FUS BBB . . .
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