A predicted binding site for cholesterol on the gabaa receptor

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  • who: Jérôme Hénin from the Laboratoire de Biochimie Théorique, CNRS, IBPC, and Université Paris Diderot, Paris, FranceComputational and Integrative Biology, Rutgers University-Camden, Camden, New Jersey have published the article: A Predicted Binding Site for Cholesterol on the GABAA Receptor, in the Journal: (JOURNAL)
  • what: The models show the possibility of previously unreported disulfide bridges linking the M1 and M3 transmembrane helices in the a and g subunits. Using the models the authors investigate cholesterol binding to intersubunit cavities of the GABAAR transmembrane domain. The authors explore the possibility that cholesterol . . .

     

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