HIGHLIGHTS
- who: from the (UNIVERSITY) have published the article: Opioids prevent regeneration in adult mammals through inhibition of ROS production, in the Journal: (JOURNAL) of 22/01/2018
- what: The authors show here that a strong production of ROS by NADPH oxidase occurs both in the spontaneous and the pharmacologically-induced regeneration processes and that its inhibition systematically prevents tissue regeneration in adult mice.
- how: To investigate both tissue regeneration and fibrotic healing in mammals the authors developed a robust and quantifiable model relying on the massive resection (around 35% of the whole tissue . . .
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