HIGHLIGHTS
- who: Pierre Barraud from the Université Maximilians University have published the research: Time-resolved NMR monitoring of tRNA maturation, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: Inspired by the NMR monitoring of PTMs in cellular environments, the authors report an original methodology to monitor RNA modifications in cellular extracts with NMR. Using yeast tRNAPhe as a model system, the authors demonstrate that multiple modification events can be monitored in yeast extract with NMR in a time-resolved fashion. The analysis has revealed a complex interplay between different modifications in the tRNA core, with the . . .
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