Rv0004 is a new essential member of the mycobacterial dna replication machinery

HIGHLIGHTS

  • who: Katherine M. Mann and colleagues from the Editor:, University of Washington have published the research: Rv0004 is a new essential member of the mycobacterial DNA replication machinery, in the Journal: (JOURNAL) of November/27,/2017
  • what: The authors provide data to support the importance of this domain by showing that the mutation of a single conserved tryptophan within DciAMtb's DnaA N-terminal-like domain leads to defects in DciAMtb's cellular activity and can affect the association of DciAMtb with DnaB. Together, this study has elucidated functions of DciAMtb that are likely applicable . . .

     

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