Review began 06/30/2022 review ended 07/18/2022 published 07/21/2022 © copyright

HIGHLIGHTS

• who: Aggregopathy and collaborators from the L EU have published the research: Review began 06/30/2022 Review ended 07/18/2022 Published 07/21/2022 © Copyright, in the Journal: (JOURNAL) of July/21,/2022
• what: The pathogenic A258P, S273I, A300T, Q304H, and A312V mutations in MT-ND4 and the F117C and I191V mutation in MT-ATP6 were expected to be pathogenic, highly conserved, and exposed to lower protein stability, indicating the most substantial harmful effect; however, these predictions need to be backed by proteomic analysis validation.
• future: Research is needed to establish . . .
  

   

  

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