HIGHLIGHTS
- who: Vincent Fregona and colleagues from the Centre de Recherches en Cancérologie de Toulouse (CRCT), Université de Toulouse, Institut National de la Santé have published the Article: Oncogene-Induced Reprogramming in Acute Lymphoblastic Leukemia: Towards Targeted Therapy of Leukemia-Initiating Cells, in the Journal: Cancers 2021, 13, 5511. of /2021/
- what: Precisely, using Cd2-Lmo2 transgenic mouse model that recapitulate the human T-ALL, the study showed that enforced expression of Lmo2 converts normal DN3 thymocytes into a self-renewing, pre-leukemic population by reprogramming a stem_cell-like gene program. The authors focused on . . .
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