A pipeline for natural small molecule inhibitors of endoplasmic reticulum stress

HIGHLIGHTS

  • who: Daniela Correia da Silva and colleagues from the Departamento QuĂ­mica, Universidade do, University of Malaya, Malaysia have published the Article: A Pipeline for Natural Small Molecule Inhibitors of Endoplasmic Reticulum Stress, in the Journal: (JOURNAL)
  • what: The authors propose a pipeline for the identification of potential ER stress inhibitors among a library of natural products. On MRC-5 fibroblasts, the authors show that the molecules that had been selected on the basis of their ability to attenuate UPR pathways were able to act upon the endpoint biological effect of this cascade, namely protein . . .

     

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