Transfer mechanism of cell-free synthesized membrane proteins into mammalian cells

HIGHLIGHTS

  • who: July et al. from the Tsinghua, China have published the research: Transfer mechanism of cell-free synthesized membrane proteins into mammalian cells, in the Journal: (JOURNAL)
  • what: The authors demonstrate that the functional nanotransfer of CFsynthesized MPs from NDs and also from Salipro particles into cellular membranes is a rather universal mechanism. The authors show the functionality of transferred GPCRs in mammalian cells and compare their localization with that of GPCR controls synthesized by transfection. While the MP transfer appears to be possible with a variety of cell lines, the authors provide the first . . .

     

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