Immunometabolism at the nexus of cancer therapeutic efficacy and resistance

HIGHLIGHTS

  • who: Javier Traba from the Departamento de Biologı´a Molecular, Centro de Biologı´a Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientı´ficas-Universidad Autónoma de Madrid (CSIC-UAM), Madrid, Spain, Cardiovascular Branch, National Heart, Lung and have published the research: Immunometabolism at the Nexus of Cancer Therapeutic Efficacy and Resistance, in the Journal: (JOURNAL)
  • what: The main reason for this is that the mitochondrial respiratory_chain is permanently damaged by NO after M1 differentiation, and accordingly, inducible NO synthase (iNOS) inhibition allows M1 cells to repolarize to M2.

SUMMARY

    The . . .

     

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