The repe initiator is a double-stranded and single-stranded dna-binding protein that forms an atypical open complex at the onset of replication of plasmid pamβ1 from gram-positive bacteria*

HIGHLIGHTS

  • who: Emmanuelle Le Chatelier from the (UNIVERSITY) have published the research: The RepE Initiator Is a Double-stranded and Single-stranded DNA-binding Protein That Forms an Atypical Open Complex at the Onset of Replication of Plasmid pAMβ1 from Gram-positive Bacteria*, in the Journal: (JOURNAL) of December/20,/2000
  • what: The authors show that RepE is monomeric in solution and binds specifically, rapidly, and durably to the origin at a unique doublestranded binding_site immediately upstream from the initiation site of DNA replication. The authors propose that RepE binding to ssDNA shifts the equilibrium . . .

     

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