The 2⠍5a/rnase l/rnase l inhibitor (rni) pathway regulates mitochondrial mrnas stability in interferon α-treated h9 cells*

HIGHLIGHTS

• who: Florence Le Roy from the cytochrome c release (58)In the same way, Yanase et_al (65) have recently shown that during IFN␣-induced apoptosis there is a release of cytochrome c from mitochondria, a decline in mitochondrial membrane potential, and caspase, activation (65). On the other hand, activation of RNase L causes caspasedependent apoptosis accompanied by cytochrome c release (66), (67). This induction of cell death by RNase L is inhibited by Bcl, (66). These results and our results show that the regulation of mitochondrial mRNAs by RNase L and its inhibitor RLI is at the . . .
  

   

  

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