Expression of cd39 identifies activated intratumoral cd8+ t cells in mismatch repair deficient endometrial cancer

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  • who: Joyce M. Lubbers et al. from the Department of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen have published the research: Expression of CD39 Identifies Activated Intratumoral CD8+ T Cells in Mismatch Repair Deficient Endometrial Cancer, in the Journal: Cancers 2022, x of 21/02/2022
  • what: The authors report that CD39+ CD8+ T cells from mismatch repair-deficient endometrial tumors are activated and characterized predominantly by expression of TNFRSF9. The authors show that CD103- CD39+ CD8+ T_cells in tumors are activated with more naïve-like cell features than their CD103 . . .

     

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