A large-scale polygenic risk score analysis identified candidate proteins associated with anxiety, depression and neuroticism

HIGHLIGHTS

  • who: Bolun Cheng from the (UNIVERSITY) have published the research work: A large-scale polygenic risk score analysis identified candidate proteins associated with anxiety, depression and neuroticism, in the Journal: (JOURNAL)
  • what: This study systematically analyzed the association between protein in brain, CSF and plasma with neuroticism, anxiety and depression. As shown in Table 2, a total of 6 candidate proteins in the study have association signals in independent proteomic studies. The authors conducted a large observational and genetic PRS analyze to systematically evaluate the correlations between proteins and complex traits (anxiety, depression and neuroticism . . .

     

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