Ufl1 promotes antiviral immune response by maintaining sting stability independent of ufmylation

HIGHLIGHTS

• who: Yijie Tao from the Ufl1fl/fl mouse was constructed by Cyagen Biotech (Suzhou, China) using CRISPR/Cas, techniques and then mated with Lyz-cre transgenic mouse, obtained from The Jackson Laboratory (Bar Harbor, ME), to generate myeloid-specific deficiencyC BL/, J mice were purchased from Joint Ventures Sipper BK Experimental Animals (Shanghai, China). Mice were kept and bred in specific-pathogen-free conditions. All animal experiments were undertaken in accordance with the National Institute of Health Guide for the Care and Use of Laboratory Animals with approval of the Scientific Investigation Board of Naval Medical University . . .
  

   

  

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