Autophagy in asthma and chronic obstructive pulmonary disease

HIGHLIGHTS

• who: Peter J. Barnes and collaborators from the College have published the article: Autophagy in asthma and chronic obstructive pulmonary disease, in the Journal: (JOURNAL) of 24/05/2022
• what: This approach has been used to measure autophagy in peripheral blood mononuclear cells, so could be developed to measure autophagic flux in bronchoalveolar lavage or sputum cells for airway disease patients.

SUMMARY

Acute exposure to cigarette smoke may activate autophagy, resulting in ciliary dysfunction and death of airway epithelial_cells, whereas in stable COPD most studies have demonstrated an impairment in autophagy . . .

 



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