The journal role of phosphoinositide e

HIGHLIGHTS

• who: Afterhyperpolarizations et al. from the DepartmentsYale University have published the research work: The Journal Role of Phosphoinositide E, in the Journal: (JOURNAL)
• what: The authors report that intracellular ejection of IP, mimics the effects of a,-agonists in prolonging the AHP and that phorbol esters, agents which potently mimic DAG (Nishizuka, 1984; Ashendel, 1985) suppress cu,-agonist-induced cell firing. The authors report now that about 80-90% of this current was sensitive to apamin and therefore conclude that 80-90% of the peak outward tail current was an apamin-sensitive ZKcCa).
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