Early changes in gene expression and inflammatory proteins in systemic juvenile idiopathic arthritis patients on canakinumab therapy

HIGHLIGHTS

• who: Arndt H. Brachat from the Istituto Giannina Gaslini, Pediatria II-PRINTO, Genoa, Italy have published the research: Early changes in gene expression and inflammatory proteins in systemic juvenile idiopathic arthritis patients on canakinumab therapy, in the Journal: (JOURNAL) of 22/04/2009
• what: Patients without fever and with a more prominent polyarticular disease course were excluded from enrollment in the original phase-3 clinical trials from which blood samples for this study were obtained.
• future: Research is needed to investigate potential differences in the disease mechanisms in patients with heterogeneous transcription profiles . . .
  

   

  

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