HIGHLIGHTS
- who: Sylvain Maenner and colleagues from the France, CNRS2578, Institut Pasteur, Paris, France have published the article: 2-D Structure of the A Region of Xist RNA and Its Implication for PRC2 Association, in the Journal: (JOURNAL) of November/25,/2009
- what: By combination of RNP affinity chromatography immunoprecipitation assays mass spectrometry and Western blot analysis the authors demonstrate that the A region can associate with components of the PRC2 complex in mouse ES cell nuclear extracts. Since the function of Xist RNA is expected to depend on its 2-D structure, studies aimed at . . .
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