Reciprocal amplification of caspase-3 activity by nuclear export of a putative human rna-modifying protein, pus10 during trail-induced apoptosis

HIGHLIGHTS

• who: Sujata Jana from the DepartmentIllinois University Washington, Seattle, WA, USA have published the paper: Reciprocal amplification of caspase-3 activity by nuclear export of a putative human RNA-modifying protein, PUS10 during TRAIL-induced apoptosis, in the Journal: (JOURNAL)
• what: The aim of this study was to determine the role of HuP10 in TRAIL-induced apoptosis. The authors propose a model for the apoptosis that includes this feedback amplification loop .
• how: The authors showed this by the reduction of caspase-3 activity using a tBID inhibitor in MDA-MB-231 cells . For . . .
  

   

  

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