Improve solubility and develop personalized itraconazole dosages via forming amorphous solid dispersions with hydrophilic polymers utilizing hme and 3d printing technologies

HIGHLIGHTS

• What: The aim of this study was to enhance the of ITZ through the utilization of various and to manufacture and programmable release ITZ tablets. In this study, various formulations were investigated. Characterization of EXT Solid States` Analysis Solid States` Analysis DSC, PLM, and PXRD studies were carried out to investigate if the ITZ in EXTs stayed DSC, PLM, PXRDinto studies werestates. carried outexperimental to investigate if the ITZ in EXTs in crystalline form orand transformed amorphous Detailed methods were mentioned in the sections "Thermalgravimetric Analysis" to "Hot-Stage Polarstayed in crystalline formfrom or transformed into amorphous . . .
  

   

  

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